The purpose of this study was to validate the framework for integrating e-learning in the Primary Schools in Bundibugyo District. The study used a cross-sectional research design with a sample size of 189 respondents (60 pupils and 129 teachers). Stratified and simple random samplings were used as sampling techniques while questionnaires and interviews were used as research instruments. This study comes up with the most effective framework for integrating ICT in primary schools. This framework captures aspects of availability of ICT resources, accessibility, and usability, with both electricity and internet connection. In addition, the framework presents teachers, learners, and administrators’ preparedness as possibilities of ICT integration. The study recommended that: Teachers should be made prepared to use integrated ICT at primary school level by receiving frequent ICT related trainings. The National Curriculum Development Centre (NCDC) should ensure that the approach is incorporated in the curriculum. The learners should be mentally prepared and gradually introduced to use integrated ICT so that they can grasp the content progressively without getting discouraged or frustrated with the ICT-enhanced learning process. Finally, the school administrators should support learners by providing ICT-related books in the library so that the learners can make further discoveries. Similarly, the school administrators and Primary Teacher Association (PTA) members to ICT technical experts in their schools to provide technical assistance such as repair, installation, maintenance, technical advice to teachers and learners.