The study aimed at evaluating the impact of internal audit activities on organizational performance and it was guided by the following objectives; To examine the relationship between risk assessment and organizational performance of Centenary Bank, to find out the role of quality management on organizational performance of Centenary Bank and to evaluate the role of control activities on the organizational performance of Centenary Bank. The study employed a descriptive correlation and cross-sectional survey design. The study adopted a survey research design because data was collected from respondents at a particular time. The participants in the study were selected using purposive sampling method and simple random sampling. From the findings, the constant 2.439, shows that keeping all other factors constant, performance of Centenary Bank was on average increase by 2.439. The coefficient 6.875 shown that a unit increase in the risk assessment would lead on average to 6.875 increases in the performance of an organization. The p-value (0.00) <0.05 (is statistically significant at 95% confidence level); this implied that; risk assessment had a significant impact on organizational performance expressed in form of profitability. The study recommends that organizations should be cautious when accumulating the internal controls because it may affect its profitability in the long run.