The purpose of this research work is to examine the extent to which the instructional materials affect student's performance in geography subject in schools in Iganga B region Iganga District. This research was based on three objectives including: to explore the views of teachers and students on the extent to which geography instructional facilities affect student performance, to examine the challenges that teachers in Iganga B region secondary schools face in accessing instructional materials and to assess the strategies that teachers use to minimize the challenges of attaining and using quality geography instructional materials. The study adopted a cross sectional survey design. The study population involved secondary schools around Iganga B region Iganga district. Five schools were randomly selected for data collection. In each school, 5 teachers and 20 students filled semi structured questionnaire. Also heads of each school and 1 secondary district education officer were interviewed. The following were the findings of the study: first, instructional materials are the key to teachers’ and students’ performance. Secondly, most secondary schools in the region suffer shortage of essential teaching and learning materials. Thirdly, the study revealed that teachers used different strategies to minimize the challenges of attaining and using quality instructional materials like borrowing books and improvation. The findings shown that in the study area 92% of the teacher responded affirm E-learning instructional materials were very important, 84% of teachers agreed that the use of maps, charts and diagrams in teaching were very important for students learning and 68% of the teacher respondents noted that the use of Instructional manuals for teaching is very important. The study recommends that the government should budget sufficient funds for improving the availability of instructional materials in all secondary schools. For further research, this study proposes that aspects of how teachers and students use instructional materials for effective teaching and learning processes need to be examined.