The study aimed at internal audit activities and organizational performance with a case study of centenary bank and it was guided by the following objectives; To examine the relationship between risk assessment and organizational performance of Centenary Bank, to find out the role of quality management on organizational performance of Centenary Bank and to evaluate the role of control activities on the organizational performance of Centenary Bank. The study employed a descriptive correlation and cross-sectional survey design. The study adopted a survey research design because data was collected from respondents at a particular time. This research survey design according to among (2015) was helpful to the researcher to attain systematic data from the sample. From the findings, the constant 2.439, shown that keeping all other factors constant, performance of Centenary Bank will on average increase by 2.439. The coefficient 6.875 shown that a unit increase in the risk assessment would lead on average to 6.875 increases in the performance of an organization. The p-value (0.00) <0.05 (is statistically significant at 95% confidence level); this implied that; risk assessment has a significant impact on organizational performance expressed in form of profitability. The coefficient 1.049 shown that a unit increase in risk assessment would lead to an average 1.049 increase in sales volume. The researcher therefore recommends that Centenary Bank should implement an effective internal auditing department to ensure that it never declines in their organizational performance.