This study was based on the relationship between public financial management and corruption practices in Uganda: A case of Wakiso district local government. The study was guided by the following objectives; To examine the causes of corruption in Wakiso, to examine the public finance management in Wakiso district Local government and to examine the relationship between public finance management and corruption practices. The study adopted a cross sectional and correlation survey design complemented with a qualitative and quantitative approach. The study population was 176 and 124 formed the sample size selected using the purposive and simple random sampling. Information was elicited using questionnaire, interview and documentary review checklist. A response rate of 63% was obtained as recommended by Amin (2005). Key findings suggested a positive significant relationship between corruption and public financial management. The study concluded that the principles of PFM are Accountability, Probity, Prudence, Equity, Transparency and Democratic consent; and corruption in PFM can directly affect a range of different development outcomes. The following were recommendations were made: Align anti-corruption measures with market, behavioral, and social forces. Adopting integrity standards is a smart business decision, especially for companies interested in doing business with the World Bank Group and other development partners. Create pathways that give citizens relevant tools to engage and participate in their governments identify priorities, problems and find solutions. Bring together formal and informal processes to change behavior and monitor progress. Use the power of technology to build dynamic and continuous exchanges between key stakeholders: government, citizens, business, civil society groups, media, academia etc. Invest in institutions and policy sustainable improvement in how a government delivers services is only possible if the people in these institutions endorse sensible rules and practices that allow for change while making the best use of tested traditions and legacies – imported models often do not work. Punishing corruption is a vital component of any effective anti-corruption effort. Keep citizens engaged on corruption at local, national, international and global levels in line with the scale and scope of corruption. Make use of the architecture that has been developed and the platforms that exist for engagement. Any good strategy must be continually monitored and evaluated to make sure it can be easily adapted as situations on the ground change.