The study was to examine the effect of school environment on students’ academic performance in Secondary school students of Tororo District. It was guided by the following objectives; to establish how availability of good teachers influences students’ academic performance, to assess the effect of school environmental factors on student’s performance and to determine howadequacy of teaching equipment influences students’ academic performance. The study employed both qualitative and quantitative approaches. The Questionnaire was the main instruments of data collection in addition to interview guide and document review. The data collected was analyzed using descriptive statistics. According to the statistical results in summary, adequacy of physical facilities improves students’ academic performance. It was concluded that presence of human resources had significant influence on students’ academic performance and presence of scholastic materials significantly influenced students’ academic performance. The study recommends school administrators too properly and appropriately plan for human resources and scholastic materials in schools and also emphasize that timetables are respected. Rewards need to be more pronounced and given enough awareness so as to enable students comprehend them better. School timetables need to provide time for counseling and guidance to students so as to prevent occurrence of offences rather than punishing the offenders.