The purpose of this study was to discuss the effect of the COVID-19 pandemic on the tourism industry in Uganda. This review utilized journals, historical records, newspaper articles, World Health Organization statistics, governmental data, and website materials on COVID-19 incidences in tourism. Secondary research was adopted in which secondary data were collected through a comprehensive literature review. The COVID-19 outbreak has significantly affected global travel and tourism. Uganda has also experienced an adverse impact on inbound and outbound tourism. International and domestic tourists have cancelled bookings in Uganda, and outbound tourism activities have also been banned. Airlines have cancelled flights, while hotels are almost completely vacant, and as a result, supporting tourism agencies are facing huge economic losses and employment cuts in Uganda. From the findings, most (45.0%) respondents indicated that their businesses have lost revenues above 2.5millions, 5.8% from 2.1 to 2.5 million, 7.9% from 1.5 to 2 million, 3.7% from 1.1 to 1.5 million, 22.8% from 500,000 to 1 million, and 14.8% below half a million. These results indicated that, cumulatively millions of shillings have been lost by tourism organizations in Uganda as a result of COVID-19 outbreak. The loss was estimated to have been recorded within a period of 4 months from the first time the outbreak was reported in China in December 2019. Once the situation has stabilized it is expected that there will be a rapid recovery, since travel demand has proven resilient in bouncing back from downturns in the past. Travel levels are expected to fully recover by 2023.