This study examined the relationship between financial inclusion and the growth of small and medium enterprises (SMEs) in Kampala, Uganda. The research was motivated by the persistent challenges faced by SMEs in accessing formal financial services, which had continued to constrain their growth potential. A cross-sectional survey design was adopted, and data were collected from 320 SME owners and managers operating within Kampala's central business district and surrounding trading areas. The findings revealed that financial inclusion, measured through access to credit, savings mobilization, digital financial services, and insurance uptake, had a statistically significant and positive effect on SME growth. The study concluded that deliberate policy interventions aimed at deepening financial inclusion were necessary for sustainable SME growth in Uganda.