The management of student records, including admission details, class allocation, and biodata, remains a largely manual and error-prone process in many Ugandan secondary schools, creating administrative inefficiencies that a dedicated, purpose-built students’ registration system can help address. This study focused on the design and implementation of a students’ registration system for Mbogo High School, guided by objectives that sought to analyze the existing manual registration process and gather user requirements, design and develop a computerized students’ registration system addressing the identified requirements, implement and test the system, and evaluate user acceptance and satisfaction with the developed system. The study adopted the Rapid Application Development methodology, comprising requirements analysis, prototyping, iterative development, and user testing, complemented by a descriptive evaluation survey administered to system users following implementation. The developed system, built using a web-based architecture with a relational database backend, provided modules for new student admission, class and stream allocation, student biodata management, and searchable record retrieval. System evaluation data were collected from a sample of 52 respondents comprising administrative staff, class teachers, and the school bursar who used the system during a one-term piloting period, and were analyzed using descriptive statistics, Pearson correlation, multiple regression, and path analysis (AMOS) grounded in the Technology Acceptance Model. Results showed high perceived ease of use (mean = 3.91) and high perceived usefulness (mean = 3.87) of the developed system, with both constructs significantly and positively correlated with user satisfaction (r = 0.612 and r = 0.671 respectively, p < 0.01). Regression analysis showed that perceived usefulness and perceived ease of use jointly explained 48.3 percent of the variance in user satisfaction (R² = 0.483). Path analysis revealed that perceived usefulness significantly mediates the relationship between perceived ease of use and user satisfaction, with a significant indirect effect (β = 0.224, p < 0.01) alongside a significant direct effect (β = 0.291, p < 0.01), yielding a total effect of 0.515. The study concludes that the developed students’ registration system was well received by users at Mbogo High School, substantially reducing the time and errors associated with the previous manual registration process, and recommends full-scale rollout, staff training, and periodic backup and system maintenance procedures.